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TAF Impact: Revolutionizing Healthcare

For Juntao Luo, finding a cure for severe sepsis is personal. The SUNY Upstate Medical University associate professor of pharmacology recalls that his brother spent several months in intensive care after contracting an infection that stimulated an extreme and life-threatening immune response.

Severe sepsis develops when an infection causes hyperinflammation, which can lead to organ failure and death. “Gladly he was young and got through it,” said Luo, noting that the experience inspired him to use his knowledge to improve survival rates for severe sepsis. Working in the Sepsis Interdisciplinary Research Center at Upstate, Luo developed a new nanoformulation that inhibits inflammation at the molecular level.

Treating sepsis as early as possible is critical to save lives. Luo’s technology includes a nanocarrier that will allow doctors to administer antibiotics with inflammation control in their offices rather than in a hospital, reducing the time between diagnosis and treatment. “The TAF investment allowed us to test the nanoformulation for proof-of-concept and get the data we need to apply for larger grants that will help us advance the technology to the next level and, ultimately, bring it to the marketplace,” Luo explained.

Luo’s innovation has potential beyond treating sepsis.  His nanocarrier is a platform technology that can be customized for individual drug molecule delivery and can be applied for severe Covid, immunotherapy cancer treatments and other therapies.

About the SUNY TAF

A significant obstacle to the commercial development of university technology is the lack of funding for promising discoveries after government-sponsored support ends and before a licensee or venture-capital support is secured. The SUNY Technology Accelerator Fund (SUNY TAF) program was established in 2011 to help bridge that gap for SUNY researchers. SUNY TAF targets critical research and development milestones—such as feasibility studies, prototyping, and testing—which demonstrate that an idea or innovation has commercial potential. The goal is to increase the likelihood of potential investors and other partners to translate these early-stage technologies into products and services with transformational capabilities.

Tags Tags: Upstate Medical University , Research , Technology Accelerator Fund

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